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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d3828aca89a484562fcc6aae1269b0a8c347b01f46ee7387e7eeeb067247d12' 
  AND token = 'CKmS42+N50ccT38RKEOhIREwyz6aF13yy27Bq35SiFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}