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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c8f3226843003b5832cdb51cb71f388ab88259e23fcb844723c7c5084597e0f' 
  AND token = 'Z6EBX2djhP3PrTh90KmQ1szu58ARXi/Wtz8F1uHDxx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}