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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3207ca01dd6e7f837d974ad3f203f283fc6b9f0a6bd82131b405459f19540609' 
  AND token = 'XfgkmuMoWmOjBatmMWBX5GYFbY0oZIx1jw4cnYtAMsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}