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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db537f0340d6bec8ac47c9d81fdb707580e77610f410f87310224aa325b84543' 
  AND token = 'AUDX9RQWoVVTTSHWwf4oa9E1g+QnwxSm3/kod8Es/4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}