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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35f7bf37a57aa7a970d5858083545c331e38f7c8c4a2dfac0ed200db5eb2473d' 
  AND token = 'S+qEXZ6cmAoP4sv+mi8TCewQLHgpJN0elIc4RmLpmWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}