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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5eb23e644fe79c53e97be96285b961e9d8add32b2c3a4cff067a5c3b4d533a3' 
  AND token = 'ZSYnKGb5SAcGZrMVWgiFFgMabSyS6W0xNA5VcyOXU4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}