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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d6ce83531f0c7067886d132f2efd379dc994b264ad9ecbdce0f37f32bdf4617' 
  AND token = '4+ouxnzmAkWmiikml05T4rEQwrWveHK033gLQS132ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}