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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38c0d3546607654b7308185ca9d4d64d1b3d47299e146065c99d581cb3c91517' 
  AND token = 'Xi4VAJxsZZhkRxXfDQEiqg0CTCIMgWLrjhL8mr3oeH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}