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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff606d035bd91803e52a699a68d263e762ef398bc8525d2454b4f64e916a26f1' 
  AND token = 'j3UqLphg74dH4wgLW5ug9f4jOSs5lIWDLUnxGYjPWF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}