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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c18964a5decc1a4f634e41c9771b771ce03de7e8868dbeb96bd3e0ffc7b26c3' 
  AND token = '8EkMsvXtoLHCU0b3PHg+C+eWzdc5B0VHzGDTZ+v7cPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}