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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a384c5137a0d0b6b23669b8d184683a2a3615ba269ca6106c5d649de66028587' 
  AND token = '+RG7bnjYcd4m8nuCwvEcs0fG412tmDCUbfv39UpkWuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}