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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75c2bb7d950b0a614cf060285d1f574a8dcb271333d42f790b5a776e04f404e2' 
  AND token = 'fdZRlSHzrN7UfQ/AMVOuY1PoF3S8WZlp4wSR+lJASAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}