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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5eadaa4294bbe0609e18df9aa78eb3bb691242d057243466e03b676bb29b6c1' 
  AND token = 'e+A7yUfwhm+k04/vGK58Qnvyy67ZPE/fSBUbnPWoBFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}