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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd950c38158894a313f22ec3c294fa20741c17dc2b8128f4dfe3c75f7fc7b2c61' 
  AND token = 'JdRWfd4f+racbMJto7bWMuKiUjdzVFixIu7R5lRIipg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}