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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52cc1575b6205eaa1968a46448f30bd54d1fb76e2e5e5ff090b7960506ba7e01' 
  AND token = 'oTTijn5yc8tuedBLtSRN59b9R3FVrK0DVysYW7zFoAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}