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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '381b9e5ce6b18ee8ea5c8f03404943ba9ceb61899393ec8311dfcc0ac69b9d5e' 
  AND token = '2VFfvN1V4qimdnWF5c49f3nAUyuGcTvhUl3xkWgTUKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}