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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c57bfa40ed93a51ac82a68a7e459fe6eca2e90c936267a4b1e0d366e0dc2280' 
  AND token = 'm+RjwxYKANRIt/MqfijnzNXVcEqFPcyE9ga9tGCMB4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}