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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f80db32cfb000f16877b355fe1cc38ad02765377b44b8eb5481f0a951d49a47' 
  AND token = 'Uzr1929SouGnekOB6UUTHgv0kMzMnJur9nCgHVosjB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}