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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '651eb1ac7fd57945483887af41171f9e14bb390df33f3df231f2f86d7a62f329' 
  AND token = 'iRAIi2RDXeLaxILWcA61XuQ+9geA+7LyUx3o7dAZ43Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}