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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7d47a8e167056c09067cf105c78b01191eb87a00b10a6cd116d2fb6ec0429a2' 
  AND token = 'teqF7jsOmhuBuTX/Ox+Oo7PiovOkSrhUUTJ3o9YGeLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}