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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f20e495375853135c163c68d9a9750884ea6c0c9adc7000a2be8a4457d5da225' 
  AND token = 'r1tFaWw9o8zD9U6wxnmXDBCZGewpema39cdanoTOfoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}