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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48311ac75e02590e522939f01f31f5712f3235ed2727dcc36a953dd676506430' 
  AND token = 'K5CkZuAuf8wJSa5nppRmbsyEN0a7O9c/H9zt/jqkiG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}