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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af64a14dd0b0ee8a29cbb27aba1c181060f828274b8a3606c7bd3bc4bc548011' 
  AND token = 'YNFLkEx3n0P2h3kk3FjxqHkAVmVWv8nLeE1og/ltfMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}