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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0ccdc5f27724c854fae43cd304c8df8acc6ceb06bac14011c0abf0b93fe0649' 
  AND token = 'azBGR1ZBXr2ht1Xhz68W4cD0dz1p52Rdca2rtfhmtko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}