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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d7518d650cdcc8979f2b4abb2da244143f0765410c35bba0ca111b17f2629f5' 
  AND token = '0p5EbQEMNwY1wGeGQowVTqvs9bDGrIVP0MiwpUyUJiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}