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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab227616fd446f2084409c61990bce42ecec25bf3572f8b44f163aed3034977f' 
  AND token = '4VP0/bkj1VExndfz/Z21z1PSr14924it1zBkCm0Lkps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}