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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d6669684bc4bda22bf04579cf923b59f22316c9d8e6fb0049d037b8b198f2f0' 
  AND token = 'UR3T7TpYFA7TOCZz05nlfHbnXRb06GlXuwi6KCxX7Xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}