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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d58e5f129b28c30a366d1a60f33d59f1bed692400bac8d3f43c8d454e10e635' 
  AND token = 'uAyxHM55wWbmsrWgxcgAm+PCJBOh/v2bVabVKAIBSHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}