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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '506d1bec332da5dde121f759bc2399bd74045a1c195c1b080d47f1de497d6321' 
  AND token = 'PU8GaFF/BGO4FWqsq0LqnK5O7RqOlfzXTlN31vKQSCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}