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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c625493a92c32ddc0a215e244eb001ba6e1e29b654e7d544fa690215e3477777' 
  AND token = 'Ens9uFaoaUGnM4th66z6+s8p85Y47NsqlzP2wPK4jAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}