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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '839351382122e3f2f38685a48d5ce565328e588169029775455e336d35e44696' 
  AND token = 'KEueY7MgWgoV8tFDXq81CH1yWzOK0FNNMf2AmJfROUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}