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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a6513733ebe6cb3afa93590d9fcf336cbf3f221a11b64174229a0f2bd17e4bd' 
  AND token = 'dNoUkvnhHnmGIJovhqx7DtXsUhqh3CXW3VJ1SWp2o/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}