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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '555b78703447ac711a8a3a738ece3fab27c793432b4b833c03cfea3e074b9842' 
  AND token = '7gWHaMIYAYmpn5kj9MjKTGd/yb2naAT7M4x3e/1CXuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}