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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dbd6ede0dd51787087d458c8232c01f1d439dd57343fff2ef0550a8a0ab5dc34' 
  AND token = 'VvXnDm2GtFY3NAtas6OIEiHT5UzJ8kBYNeihSfMSvWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}