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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e86a3f4049c84b3e5b05f741d9088ccba49dc194084ef906627a6822d1d7c1e3' 
  AND token = 'X9BKqTCHNtTlngM2YpYzunEg2yWFd835nuzlbcFRijM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}