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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef8cf50a90b57504068f541f4d5e347822a23d926b6d732bcf7b4287c5907368' 
  AND token = 'pVuQpRkIhPx0Wdl/gqMXWT6OW36bmsD85gSzMfjHc9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}