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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da4afa36fed46c059962217c35b9ea26ab8e86c4054a6296b4d141349e6cb999' 
  AND token = 'akU7G6G/1uqSuau63FzF/hRJW8WRK7OyTvkmVaDy9R4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}