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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03d7226d0967ecaa6850dec4871e0396ec60ec7f002e37cb9d0b6f020103348c' 
  AND token = 'AZRHHFZvOFE48CYbb1+CiR9gq/eV6ue5yEXf6QvP/nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}