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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40a5bb7cff28847e5bd2cd7474f13cb3d9a174b720999bbada8ed8784acd109d' 
  AND token = 'JQU+HRgoEZQ3tpnoZ48+C5p7MDTgsVdC2e9doLGlSxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}