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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f7e64dec550223632364c1eef6b3fb71d81317353725bdfadce44e8dc5901cb' 
  AND token = '7PnY2iSrL7KoudXCMy5kp9L1G0NNMSWYnYqf+RHf6qI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}