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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f7262e273a6ff476c63a2f0ca8261cf43d069dfb7bb2418d82bc9b4b7cf8bfd' 
  AND token = 'dTbXvhoInBGsu1Rek7cbTc8P/MxOEteB9ajMNPTgqT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}