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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4e7548cc888c87ff4048de9b0b78a18a225a4226050b4b6830ecdfe48fb9151' 
  AND token = 'jpPEnA3gy8ZOKvw2/aOwwnS0FsJ4VWUhZOZ11ihHy4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}