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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '454df53d16dba43f98d469b2c70be20c3bf7aca65352ceafcf00e850bb4f3b1c' 
  AND token = 'PA9LpS0H+D6mUtupkucZjJ0p/rA/h+mnXd7wrpVeS3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}