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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ea02d38e3e0ca287394097dc08ee2c648de64f25b4e30602dd6bf0eefc023cd' 
  AND token = 'LPJKnvWGqvV90FMBJSMrz5vle+1V+r85LSTn8bulzn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}