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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '580c6f13b686530787febba82c4cf2effc60195e1d0e7e32593448820c31ed4a' 
  AND token = '8ILOTGkBxJeW25oFa2Ax5l3e1tf96ptdXCZgCnBoGn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}