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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2197f16a6d704ec5571b46a82efae5b8e1ed7fd916056d663d9e6d4e15230fde' 
  AND token = 'Y7MlyDPgYX5wH9EBGQHA0/iqvfem+n2k9dQlkog0BBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}