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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a552d931f78c5935c6a6edc785cff7afce3bec3e5351feb5a83cb64c2c03c99' 
  AND token = 'nwPTtxs2c53b1UFQOXNFpMosLlTBAJW30UbeTFkMHCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}