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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7688ceea653b3e01c7b1112f7461f54a68bd88de53179aa3314b4730cb27bca4' 
  AND token = 'NFMP2GVM55+3KEO8QFWp9Go2uN7ke8P50Q6v5lis+K0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}