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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd7b44442f8570fd49fb399e3196f5d07d8cd7a21544830589a2d41191012264' 
  AND token = 'bnunco1Cqqcp2gHAkChBp1rB9CCnU4JdEXDjITZWHrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}