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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b925573a027cab3af03944ba37a37a5a45ef2baf07f88ad51be2abee4a9e286' 
  AND token = 'owP+OT09ImI+yikOG91CHYDdDPT3KflgVpCCobweJes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}